Anti-RGS9L antibodies are used in antigen-specific immunodetection in biological samples. The target RGS9L is a known alias name of the protein regulator of G protein signaling 9, encoded by the RGS9 gene in humans. This 674-amino acid residue protein is known to inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It is localized to the membrane of the cell and features phosphorylated post-translational modifications. In terms of tissue expression, it is reported to be highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Other synonyms for RGS9L include PERRS and PERRS1.