Anti-TRE antibodies enable researchers to detect and measure the TRE antigen in biological samples. This target is a reported synonym of the TREH gene, which encodes trehalase. This protein is known to function in organ morphogenesis, among other biological roles. The human version of TRE has a canonical amino acid length of 583 residues and a protein mass of 66.6 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the cell membrane of cells and notably expressed in the small intestine, kidney, and duodenum. TRE is a member of the Glycosyl hydrolase 37 protein family.