Anti-PPCD antibodies are used in antigen-specific immunodetection in biological samples. The target PPCD is a known alias name of the protein collagen type VIII alpha 2 chain, encoded by the COL8A2 gene in humans. This 703-amino acid residue protein is reported to be a macromolecular component of the subendothelium. It is localized to the extracellular matrix and is secreted of the cell and features cleaved post-translational modifications. In terms of tissue expression, it is notably expressed in the subendothelium of large blood vessels.