Anti-OGA antibodies are used in the immunodetection of the protein O-GlcNAcase. In humans, the canonical protein has a reported length of 916 amino acid residues and a mass of 102.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the Glycosyl hydrolase 84 protein family, it is known to be involved with metabolic processes. Post-translational modifications have been described, including protein cleavage. Synonyms for this target antigen include MGEA5, NCOAT, protein O-GlcNAcase, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, and MEA5.