Anti-Ism antibodies enable researchers to detect and measure the Ism antigen in biological samples. This target is a reported synonym of the ISM1 gene, which encodes isthmin 1. This protein is known to function in the regulation of angiogenesis, among other biological roles. The human version of Ism has a canonical amino acid length of 464 residues and a protein mass of 52.1 kilodaltons. It is reported to be a secreted protein. Ism is a member of the Isthmin protein family.