KMT2B is a symbol for the gene, Lysine (K)-specific methyltransferase 2B, in humans. Other names include: Histone-lysine N-methyltransferase 2B; Lysine N-methyltransferase 2B; Myeloid/lymphoid or mixed-lineage leukemia protein 4; Trithorax homolog 2; WW domain-binding protein 7; WBP-7; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; CXXC10; HRX2; MLL1B; WBP7. The encoded protein is an enzyme with an amino acid length of 2715 and a mass of 293.5 kDa. KMT2B is a member of the Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, TRX/MLL subfamily. This gene shares homology with other species, including: Mouse, Rat, Frog.