Anti-ADRA2A antibodies are used in the immunodetection of the protein adrenoceptor alpha 2A. In humans, the canonical protein has a reported length of 465 amino acid residues and a mass of 50.6 kDa. Its subcellular localization is in the cell membrane. A member of the G-protein coupled receptor 1 protein family, ADRA2A is known to be involved with cytoskeleton organization and GPCR signaling pathways. Post-translational modifications have been described, including glycosylation. The ADRA2A marker can be used to identify Ureter Vascular Smooth Muscle Cells and Bladder Vascular Smooth Muscle Cells.* Synonyms for this target antigen include ADRA2R, ADRAR, ALPHA2AAR, ZNF32, alpha-2A adrenergic receptor, and ADRA2. ADRA2A gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4