alpha-2a Adrenergic Receptor Antibody PA1-048 from Thermo Fisher Scientific

Product Specs
Itemalpha-2a Adrenergic Receptor Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-048
NCBI Gene AliasesADRAR, Adra-2a, Adra-2, alpha(2A)AR, ADRA2, RATRG20, alpha2A-AR, ALPHA2AAR, alpha2A, CA2-47, RG20, ZNF32, alpha2-C10, ADRA2R
ClonalityPolyclonal
HostRabbit
Conjugate/TagUnconjugated
Targetalpha-2a Adrenergic Receptor
FormatPBS with 1mg/mL BSA and 0.05% sodium azide
ReactivityHu, Ms, Rt
Concentration0.6 mg/mL
ImmunogenSynthetic peptide corressponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR
Antibody TypePrimary
Storage-20°C, Avoid Freeze/Thaw Cycles
PurityAntigen affinity chromatography
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
IsotypeIgG
ApplicationsWB, IHC-p
NCBI Full Gene Nameadrenoceptor alpha 2A, adrenergic receptor, alpha 2a
Quantity100 µL

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(1) Histone lysine methyltransferases MLL3 and MLL4 direct gene expression to produce platelets efficientlyNat CommunJuly 1, 2025Guozhen Gao, Josimar Dornelas Moreira, Prosun Das, Kevin Lin, Kai Ge, Taiping Chen, Yue Lu, Margarida A. Santosthe Wysocka lab, Stanford University), 1:500, anti-PTIP (#ABE1877, Millipore) 1:1000, anti-Adra2a (#PA1-048, Thermo Fisher Scientific) 1:1000, anti-Rgs10 (#PA5-97304, Thermo Fisher Scientific) 1:1000, anti-α

(2) An immunohistochemical protocol for visualizing adrenergic receptor subtypes in the rhesus macaque hippocampusJournal of Neuroscience MethodsJune 1, 2025Kelsey E. McDermott, Carol A. BarnesHuman",P,P α2a,Antibodies.com,A94129,Rabbit,Human,F,NA α2a,R & D Systems,Clone: 1006614,Mouse,NA,F,NA α2a,Invitrogen,PA5-18475,Goat,NA,F,NA α2a,Invitrogen,PA1-048,Rabbit,"Mouse, Rat, Human",F,NA α2a,Abcam,AB85570,Rabbit,"Mouse, Rat, Human",P,P α2a,Novus,NBP3-10657,Rabbit,NA,P,F* α2a,Bioss,BS1062R,Rabbit,NA,P,P β1,Abcam,AB77189,Goat,"Mouse,

(3) β-Adrenergic Blockers Increase cAMP and Stimulate Insulin Secretion Through a PKA/RYR2/TRPM5 Pathway in Pancreatic β-Cells In VitroPharmacol Res PerspectApril 13, 2025Naoya Murao, Risa Morikawa, Yusuke Seino, Kenju Shimomura, Yuko Maejima, Yuichiro Yamada, Atsushi Suzukiprobed with polyclonal anti‐ADRA2A rabbit antibody (Thermo Fisher Scientific, Waltham, MA, USA, Cat# PA1‐048, RRID:AB_2225243) overnight at 4°C. To detect RYR2 phosphorylation, the lysate was separated on a 5%

(4) Degradation products of magnesium implant synergistically enhance bone regeneration: Unraveling the roles of hydrogen gas and alkaline environmentBioactive materialsApril 1, 2025An Y, Zhang H, Zhang S, Zhang Y, Zheng L, Chen X, Tong W, Xu J, Qin L.(ab137869, Abcam, 1:300), ADRA1 (PA1-047, Thermo Fisher Scientific, 1:200), ADRA2 (Thermo Fisher Scientific, PA1-048, 1:200), ADRB1 (Thermo Fisher Scientific, PA5-95742, 1:200), ADRB2 (Abcam, ab182136, 1:200), ADRB3 (Abcam,

(5) Neuro-Mesenchymal Interaction Mediated by a β2-Adrenergic Nerve Growth Factor Feedforward Loop Promotes Colorectal Cancer ProgressionCancer discoveryJanuary 13, 2025Kobayashi H, Iida T, Ochiai Y, Malagola E, Zhi X, White RA, Qian J, Wu F, Waterbury QT, Tu R, et al.polyclonal anti-NGF (1:1000 for WB, A13922, ABclonal), Rabbit polyclonal anti-ADRA2A (1:500 for WB, PA1–048, Invitrogen), and Rabbit polyclonal anti-ACTB (1:1000 for WB, 4967, CST). Cell culture Human primary

(6) Capillary Western Immunoassay Optimization of Estrogen Related Factors in Human Subcutaneous Adipose TissueMethods and protocolsApril 15, 2022Hill JL, McIver KB, Katzer K, Foster MT.(NBP2-01952, Novus Biologicals, Littleton, CO, USA); HSD17ß4 (VMA00380, Bio-Rad, Herceules, CA, USA); ARα2 (PA1-048, Invitrogen, Waltham, MA USA); ARß2 (ab182136, Abcam). The following anti-rabbit (DM-001 ProteinSimple

(7) Singular versus combinatory glucose-sensitive signal control of metabolic sensor protein profiles in hypothalamic astrocyte cultures from each sexTranslational neuroscienceJanuary 1, 2022Alhamyani A, Napit PR, Bheemanapally K, Sylvester PW, Briski KP.Cell Signaling Technol.), α1AR (1:1,000; prod. no. PA1-047; Thermo Fisher Scientific), α2AR (1:1,000; prod. no. PA1-048; Thermo Fisher Scientific), or β1AR (1:1,000; prod. no. NBP1-59007; Novus Biologicals, Littleton, CO),

(8) Presynaptic Release-Regulating Alpha2 Autoreceptors: Potential Molecular Target for Ellagic Acid Nutraceutical PropertiesAntioxidants (Basel, Switzerland)November 4, 2021Romeo I, Vallarino G, Turrini F, Roggeri A, Olivero G, Boggia R, Alcaro S, Costa G, Pittaluga A.PVDF membranes. Membranes were probed with rabbit α2A adrenergic receptor polyclonal antibody (1:250, PA1-048, Invitrogen, Thermo Fisher Scientific, Waltham, MA, USA) and with mouse α2C adrenergic receptor monoclonal

(9) Carotid smooth muscle contractility changes after severe burnScientific reportsSeptember 10, 2021DeSpain K, Rosenfeld CR, Huebinger R, Wang X, Jay JW, Radhakrishnan RS, Wolf SE, Song J.adrenergic receptor antibodies with dilution factors including α-1a (cat#PA1-047, 1:200), α-2a (cat# PA1-048, 1:75), β1 (cat#BS-0498R, 1:275), and β2 (cat#13096-1-AP, 1:275) were purchased from Fisher Scientific.

(10) Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidanceNature communicationsSeptember 8, 2020Eagle AL, Manning CE, Williams ES, Bastle RM, Gajewski PA, Garrison A, Wirtz AJ, Akguen S, Brandel-Ankrapp K, Endege W, et al.using primary antibodies against FosB (ab11959; 1:1000; Abcam), GFP (ab5450; 1:1000; Abcam), and α2AAR (PA1-048; 1:1000; Invitrogen), and secondary antibodies (1:200; Jackson Immunoresearch) conjugated to fluorescent

(11) Zerumbone Modulates α_2A-Adrenergic, TRPV1, and NMDA NR2B Receptors Plasticity in CCI-Induced Neuropathic Pain In Vivo and LPS-Induced SH-SY5Y Neuroblastoma In Vitro ModelsFrontiers in pharmacologyJanuary 1, 2020Chia JSM, Izham NAM, Farouk AAO, Sulaiman MR, Mustafa S, Hutchinson MR, Perimal EK.for 1 h. After blocking, blots were incubated overnight with anti- a2A adrenergic receptor (1:500, PA1-048, Thermo Fisher Scientiﬁc, USA), anti-VR1 (1:1,000, ab31895, Abcam, USA), or anti-NR2B (1:1,000, ab65783,

(12) Norepinephrine Regulation of Adrenergic Receptor Expression, 5' AMP-Activated Protein Kinase Activity, and Glycogen Metabolism and Mass in Male Versus Female Hypothalamic Primary Astrocyte CulturesASN neuroJanuary 1, 2020Ibrahim MMH, Bheemanapally K, Sylvester PW, Briski KP.

(13) Morphological correlates of sex differences in acoustic startle response and prepulse inhibition through projections from locus coeruleus to cochlear root neuronsBrain structure & functionNovember 1, 2017Hormigo S, Gómez-Nieto R, Sancho C, Herrero-Turrión J, Carro J, López DE, Horta-Júnior JACE.

(14) Brimonidine Protects Auditory Hair Cells from in vitro-Induced Toxicity of GentamicinAudiology & neuro-otologyJanuary 1, 2017Cortada M, Levano S, Bodmer D.Switzerland); GAPDH at 1:5,000 (ab8245; Abcam, Labforce AG, Nunningen, Switzerland), and α2a-AR at 1:500 (PA1-048; Affinity Bioreagents, Golden, CO, USA). OC Dissection All animal procedures were carried out in Basel,

(15) Single-cell analysis of long non-coding RNAs in the developing human neocortexGenome biologyApril 14, 2016Liu SJ, Nowakowski TJ, Pollen AA, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, et al.were collected using a Leica CM3050S cryostat. Primary antibody: ADRA2A (1:100, Thermo Scientific, PA1-048). Heat-induced antigen retrieval was performed in 10 mM sodium citrate buffer, pH 6. Binding was revealed

(16) Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortexNature biotechnologyOctober 1, 2014Pollen AA, Nowakowski TJ, Shuga J, Wang X, Leyrat AA, Lui JH, Li N, Szpankowski L, Fowler B, Chen P, et al.SYNC we did not perform antigen retrieval. Primary antibodies against ADRA2A (1:100, Thermo Scientific PA1-048), CAMKV (1:100, Novus Biologicals NBP1-68097), EGR1 (1:50, Cell Signaling 41535), C-FOS (1:100, Santa Cruz

(17) Immunohistochemical localization of α2-adrenergic receptors in the neonatal rat cochlea and the vestibular labyrinthJournal of molecular neuroscience : MNNovember 1, 2013Cai J, Li J, Mao Y, Bai X, Xu L, Wang H.

(18) Stimulation of α(2A)-adrenoceptors promotes the maturation of dendritic spines in cultured neurons of the medial prefrontal cortexMolecular and cellular neurosciencesFebruary 1, 2012Ren WW, Liu Y, Li BM.

(19) Functional interaction between alpha2-adrenoceptors, mu- and kappa-opioid receptors in the guinea pig myenteric plexus: effect of chronic desipramine treatmentEuropean journal of pharmacologyDecember 28, 2006Luca Canciani, Cristina Giaroni, Elena Zanetti, Daniela Giuliani, Rossana Pisani, Elisabetta Moro, Marco Trinchera, Francesca Crema, Sergio Lecchini, Gianmario Frigo

(20) Alpha2-adrenergic regulation of NO production alters postoperative intestinal smooth muscle dysfunction in rodentsAmerican journal of physiology. Gastrointestinal and liver physiologySeptember 1, 2004Kreiss C, Toegel S, Bauer AJ.

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alpha-2a Adrenergic Receptor Antibody from Thermo Fisher Scientific

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alpha-2a Adrenergic Receptor Antibody from Thermo Fisher Scientific

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