Anti-AP1S3 antibodies are used in the immunodetection of the protein adaptor related protein complex 1 subunit sigma 3. In humans, the canonical protein has a reported length of 154 amino acid residues and a mass of 18.3 kDa. Its subcellular localization is in the cytoplasmic vesicles, Golgi, and membrane. Up to 4 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the Adaptor complexes small subunit protein family, AP1S3 is known to be involved with vesicle-mediated transport. The AP1S3 gene has been associated with the disease, Psoriasis. Synonyms for this target antigen include adapter-related protein complex 1 subunit sigma-1C, adaptor protein complex AP-1 sigma-1C subunit, adaptor related protein complex 1 sigma 3 subunit, and AP-1 complex subunit sigma-3. AP1S3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA, Western Blot, and Immunohistochemistry are common applications for AP1S3 antibodies.