Anti-IL-37 antibodies enable researchers to detect and measure the IL-37 antigen in biological samples. This target is a reported synonym of the IL37 gene, which encodes interleukin 37. This protein is known to function in the cellular response to lipopolysaccharides and cytokine-mediated signaling pathways, among other biological roles. The human version of IL-37 has a canonical amino acid length of 218 residues and a protein mass of 24.1 kilodaltons, although 5 isoforms have been identified. It is reported to be localized in the nucleus, cytoplasm, and is secreted of cells. Other names for this target antigen include FIL1, FIL1(ZETA), and FIL1Z. A number of IL-37 antibodies have been mentioned in research publications and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.