Anti-IL-27 antibodies are protein reagents that detect specific antigens. The IL-27 antigen is another term for the human protein interleukin 27, encoded by the IL27 gene. The protein is reported to associate with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. Canonically, it has an amino acid length of 243 residues and a mass of 27.5 kilodaltons. It is a secreted protein and it is reported to be expressed in monocytes and in the placenta. The IL-27 protein is a member of the IL-6 protein superfamily. Other alias names for IL-27 include interleukin-27 subunit alpha, IL-27 p28 subunit, and IL-27 subunit alpha. Over 130 citations in the literature describe the use of IL-27 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.