Anti-EME2 antibodies are used in the immunodetection of the protein essential meiotic structure-specific endonuclease subunit 2. In humans, the canonical protein has a reported length of 379 amino acid residues and a mass of 41.2 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. A member of the EME1/MMS4 protein family, EME2 is known to be involved with DNA damage pathways. Synonyms for this target antigen include SLX2 structure-specific endonuclease subunit homolog B, essential meiotic endonuclease 1 homolog 2, homolog of yeast EME1 endonuclease 2, and probable crossover junction endonuclease EME2. EME2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some EME2 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.