Anti-WAPL antibodies are used in the immunodetection of the protein WAPL cohesin release factor. In humans, the canonical protein has a reported length of 1190 amino acid residues and a mass of 132.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the WAPL protein family, WAPL is a reported regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Synonyms for this target antigen include KIAA0261, WAPAL, wings apart-like protein homolog, friend of EBNA2 (Epstein-Barr virus nuclear protein 2), friend of EBNA2 protein, and FOE. WAPL gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of WAPL antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.