Anti-KLRC1 antibodies are used in the immunodetection of the protein killer cell lectin like receptor C1. In humans, the canonical protein has a reported length of 233 amino acid residues and a mass of 26.3 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the NK cells. KLRC1 is known to be involved with adaptive immune responses and receptor-mediated signaling pathways. Post-translational modifications have been described, including phosphorylation and glycosylation. The KLRC1 marker can be used to identify Natural Killer Cells.* Synonyms for this target antigen include NKG2, NKG2A, NKG2-A/NKG2-B type II integral membrane protein, C-lectin type II protein, CD159 antigen-like family member A, and CD159A.
*HuBMAP Human Reference Atlas v1.4