Anti-ORC3 antibodies are used in the immunodetection of the protein origin recognition complex subunit 3. In humans, the canonical protein has a reported length of 711 amino acid residues and a mass of 82.3 kDa. Its subcellular localization is in the nucleus and chromosomes. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the ORC3 protein family, ORC3 is a known component of the origin recognition complex (ORC) that binds origins of replication. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include LATHEO, ORC3L, homolog of latheo, Drosophila, origin recognition complex subunit Latheo, origin recognition complex, subunit 3 honolog, and LAT. ORC3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ORC3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.