Anti-VARS2 antibodies are used in the immunodetection of the protein valyl-tRNA synthetase 2, mitochondrial. In humans, the canonical protein has a reported length of 1063 amino acid residues and a mass of 118.5 kDa. Its subcellular localization is in the mitochondria. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. It is a member of the Class-I aminoacyl-tRNA synthetase protein family. The VARS2 gene has been associated with the disease, Combined oxidative phosphorylation deficiency. Synonyms for this target antigen include valine tRNA ligase 2, mitochondrial (putative), valyl-tRNA synthetase like, and valine--tRNA ligase, mitochondrial. VARS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some VARS2 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.