Anti-AHSP antibodies are used in the immunodetection of the protein alpha hemoglobin stabilizing protein. In humans, the canonical protein has a reported length of 102 amino acid residues and a mass of 11.8 kDa. Its subcellular localization is in the cytoplasm. It is reported to be expressed in blood and bone marrow. A member of the AHSP protein family, AHSP is known to act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development.
The AHSP marker can be used to identify Erythroid Lineage Cells.* Synonyms for this target antigen include ERAF, alpha hemoglobin stabilising protein, erythroid differentiation associated factor, erythroid differentiation-related factor, and EDRF. AHSP gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Some AHSP antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4