Anti-ProSAP2 antibodies enable researchers to detect and measure the ProSAP2 antigen in biological samples. This target is a reported synonym of the SHANK3 gene, which encodes SH3 and multiple ankyrin repeat domains 3. This protein is known to function in MAPK cascade signaling pathways, among other biological roles. The human version of ProSAP2 has a canonical amino acid length of 1731 residues and a protein mass of 184.7 kilodaltons. It is reported to be localized in the cytoplasm of cells and notably expressed in many tissues, such as the caudate and cerebellum.