Anti-CLDN22 antibodies are used in the immunodetection of the protein claudin 22. In humans, the canonical protein has a reported length of 220 amino acid residues and a mass of 24.5 kDa. Its subcellular localization is in the cell membrane. A member of the Claudin protein family, CLDN22 is known to play an important role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Synonyms for this target antigen include CLDN21. CLDN22 gene orthologs have been reported in the mouse and chimpanzee species. Western Blot is the most common application for the CLDN22 antibodies listed below. ELISA and Immunofluorescence are also common applications.