Anti-RPIA antibodies are used in the immunodetection of the protein ribose 5-phosphate isomerase A. In humans, the canonical protein has a reported length of 311 amino acid residues and a mass of 33.3 kDa. It is notably widely expressed in many tissue types. A member of the Ribose 5-phosphate isomerase protein family, RPIA is known to catalyze the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non-oxidative branch of the pentose phosphate pathway. The RPIA gene has been associated with the disease, Ribose 5-phosphate isomerase deficiency. Synonyms for this target antigen include RPIAD, ribose-5-phosphate isomerase, phosphoriboisomerase, ribose 5-phosphate epimerase, and RPI. RPIA gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some RPIA antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.