PMCA, or ATPase, Ca++ transporting, plasma membrane 1, is a human gene encoded by ATP2B1. It may also be known as: Plasma membrane calcium-transporting ATPase 11; Plasma membrane calcium ATPase isoform 1; Plasma membrane calcium pump isoform 11kb. The encoded protein is an enzyme with an amino acid length of 1258 and a mass of 138.8 kDa. Other isoforms may exist. PMCA is a member of the Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIB subfamily. Homologs of this gene exist in other organisms, including: Mouse, Rat, Frog, Chicken.