Anti-IL36A antibodies are used in the immunodetection of the protein interleukin 36 alpha. In humans, the canonical protein has a reported length of 158 amino acid residues and a mass of 17.7 kDa. Its subcellular localization is in the cytoplasm and is secreted. It is reported to be expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. A member of the IL-1 protein family, IL36A is a reported to be a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Synonyms for this target antigen include FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6, FIL1 epsilon, IL-1 epsilon, and FIL1. IL36A gene orthologs have been reported in the mouse species. A number of IL36A antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.