Anti-GluR2 antibodies enable researchers to detect and measure the GluR2 antigen in biological samples. This target is a reported synonym of the GRIA2 gene, which encodes glutamate ionotropic receptor AMPA type subunit 2. This protein is known to function in chemical synaptic transmission and signal transduction pathways, among other biological roles. The human version of GluR2 has a canonical amino acid length of 883 residues and a protein mass of 98.8 kilodaltons, although 4 isoforms have been identified. It is reported to be localized in the ER and cell membrane of cells and notably expressed in the hippocampus, cerebral cortex, cerebellum, and caudate. GluR2 is a member of the Glutamate-gated ion channel (TC 1.A.10.1) protein family.