Anti-TXNDC2 antibodies are used in the immunodetection of the protein thioredoxin domain containing 2. In humans, the canonical protein has a reported length of 553 amino acid residues and a mass of 60.4 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to have testis-specific expression. TXNDC2 is suspected to be plays a regulatory role in sperm development. Synonyms for this target antigen include sperm-specific thioredoxin 1, spermatid-specific thioredoxin-1, sptrx-1, testicular tissue protein Li 215, thioredoxin domain containing 2 (spermatozoa), and thioredoxin domain-containing protein 2. TXNDC2 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Some TXNDC2 antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. In addition, Western Blot is also a common application.