Anti-Septin 5 antibodies are used in the immunodetection of the protein encoded by the SEPTIN5 gene. In humans, the canonical protein has a reported length of 369 amino acid residues and a mass of 42.8 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is notably expressed at high levels in the CNS, as well as in heart and platelets. The septin 5 protein is a member of the Septin GTPase protein family. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include CDCREL-1, CDCREL1, H5, HCDCREL-1, PNUTL1, cell division control related protein 1, peanut-like 1, and CDCREL.