Fig 1: The quantitative fold changes in the expression of the target gene (HOXA10, VEGF-A, c-Kit, Oct-4, IL-1ß, IL-10, and NF-?B) relative to the internal control gene (ß-actin) were analyzed using real-time PCR. (A) Significantly increased expression of HOXA10 in the PRP-treated group compared to the ethanol group, but no significant change in the expression of VEGF-A. (B) Significantly increased expression of the c-Kit gene in the PRP-treated group compared to the ethanol group, but no significant change in the expression of the Oct-4 gene. (C) Significantly increased expression of IL-1ß in the ethanol group when compared to the other groups, but no significant change in the expressions of IL-10 and NF-?B on comparison of the ethanol group and the PRP-treated group. Statistical comparisons of groups are based on the Mann-Whitney test, with statistical significance defined as p<0.05. *Significant when compared to the control, †Significant when compared between the ethanol group and the PRP-treated group. HOXA10, homeobox A10; VEGF-A, vascular endothelial growth factor-A; Oct-4, octamer-binding transcription factor 4; IL, interleukin; NF-?B, nuclear factor-?B; PCR, polymerase chain reaction; PRP, platelet-rich plasma.