Anti-FHOD1 antibodies are used in the immunodetection of the protein formin homology 2 domain containing 1. In humans, the canonical protein has a reported length of 1164 amino acid residues and a mass of 126.6 kDa. Its subcellular localization is in the cytoplasm. It is ubiquitously expressed across many tissue types. A member of the Formin homology protein family, FHOD1 is known to be required for the assembly of F-actin structures, such as stress fibers. Post-translational modifications have been described, including phosphorylation.
The FHOD1 marker can be used to identify Splenic Littoral Cells.* Synonyms for this target antigen include FH1/FH2 domain-containing protein 1, formin homolog overexpressed in spleen 1, and FHOS. FHOD1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of FHOD1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4