Anti-IBSP antibodies are used in the immunodetection of the protein integrin binding sialoprotein. In humans, the canonical protein has a reported length of 317 amino acid residues and a mass of 35.1 kDa. It has been described to be a secreted protein. IBSP is known to bind tightly to hydroxyapatite. Post-translational modifications have been described, including O-glycosylation, N-glycosylation and sulfation. Synonyms for this target antigen include BSP, BSP-II, SP-II, bone sialoprotein 2, BSP II, bone sialoprotein II, cell-binding sialoprotein, and BNSP. IBSP gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 90 citations in the literature describe the use of IBSP antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.