HSD17B2 encodes the human gene, Hydroxysteroid (17-beta) dehydrogenase 2. It may also be known as: Estradiol 17-beta-dehydrogenase 2; 17-beta-hydroxysteroid dehydrogenase type 2; 17-beta-HSD 2; Microsomal 17-beta-hydroxysteroid dehydrogenase; Short chain dehydrogenase/reductase family 9C member 2; Testosterone 17-beta-dehydrogenase; Estradiol 17-beta-dehydrogenase 2 ; short chain dehydrogenase/reductase family 9C, member 2; EDH17B2; SDR9C2. The encoded protein is an enzyme with an amino acid length of 387 and a mass of 42.8 kDa. Other isoforms may exist. HSD17B2 is a member of the Short-chain dehydrogenases/reductases (SDR) family. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.