Anti-NCDN antibodies are used in the immunodetection of the protein neurochondrin. In humans, the canonical protein has a reported length of 729 amino acid residues and a mass of 78.9 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is found to be highly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. A member of the Neurochondrin protein family, NCDN is suspected to be involved in signal transduction in the nervous system, via increasing cell surface localization of GRM5/mGluR5 and positively regulating its signaling. Post-translational modifications have been described, including palmitoylation. Synonyms for this target antigen include NEDIES and norbin. NCDN gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of NCDN antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, and Immunofluorescence are also common applications.