Anti-KLF5 antibodies are used in the immunodetection of the protein KLF transcription factor 5. In humans, the canonical protein has a reported length of 457 amino acid residues and a mass of 50.8 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 4 different isoforms for this protein. It is found to be preferentially expressed in testis and placenta. A member of a the Krueppel C2H2-type zinc-finger protein family, KLF5 is reported to be a transcription factor that binds to GC box promoter elements. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include CKLF, IKLF, Krueppel-like factor 5, (intestinal Kruppel-like factor, BTE-binding protein 2, and BTEB2.