Anti-CNIH4 antibodies are used in the immunodetection of the protein cornichon family AMPA receptor auxiliary protein 4. In humans, the canonical protein has a reported length of 139 amino acid residues and a mass of 16.1 kDa. Its subcellular localization is in the ER and membrane. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Cornichon protein family, CNIH4 is known to be involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery. Synonyms for this target antigen include HSPC163, protein cornichon homolog 4, cornichon homolog 4, and CNIH2. CNIH4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA, Western Blot, and Immunohistochemistry are common applications for CNIH4 antibodies.