Anti-G3BP2 antibodies are used in the immunodetection of the protein G3BP stress granule assembly factor 2. In humans, the canonical protein has a reported length of 482 amino acid residues and a mass of 54.1 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. G3BP2 is reported to be a scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling. Post-translational modifications have been described, including methylation and protein cleavage. Synonyms for this target antigen include GAP SH3 domain-binding protein 2, GTPase activating protein (SH3 domain) binding protein 2, Ras-GTPase activating protein SH3 domain-binding protein 2, and ras GTPase-activating protein-binding protein 2.