Anti-FNDC1 antibodies are used in the immunodetection of the protein fibronectin type III domain containing 1. In humans, the canonical protein has a reported length of 1894 amino acid residues and a mass of 205.6 kDa. It has been described to be a secreted protein. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. FNDC1 is believed to be an activator of G protein signaling. Post-translational modifications have been described, including glycosylation.
The FNDC1 marker can be used to identify Hippocampal Gyrus CA1-3 Neurons and Cerebellar Inhibitory Neurons.* Synonyms for this target antigen include activation-associated cDNA protein, expressed in synovial lining protein, fibronectin type III domain containing 2, and fibronectin type III domain-containing protein 1. FNDC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some FNDC1 antibodies may have been used in research and have associated citations. Immunofluorescence is a widely used application for these antibodies. Immunocytochemistry and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4