Anti-GMPR2 antibodies are used in the immunodetection of the protein guanosine monophosphate reductase 2. In humans, the canonical protein has a reported length of 348 amino acid residues and a mass of 37.9 kDa. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. A member of the IMPDH/GMPR protein family, GMPR2 is known to catalyze the irreversible NADPH-dependent deamination of GMP to IMP. Synonyms for this target antigen include guanosine 5'-monophosphate oxidoreductase 2, guanosine monophosphate reductase isolog, and GMP reductase 2. GMPR2 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. These GMPR2 antibodies are widely used in Western Blot experiments, among other applications.