Anti-CLC antibodies are used in the immunodetection of the protein Charcot-Leyden crystal galectin. In humans, the canonical protein has a reported length of 142 amino acid residues and a mass of 16.5 kDa. Its subcellular localization is in the cytoplasm. It is noted to be expressed abundantly in the bone marrow. CLC is reported to regulate immune responses through the recognition of cell-surface glycans. The CLC marker can be used to identify Eosinophils, Basophils, and Mast Cells.* Synonyms for this target antigen include Gal-10, LGALS10, LGALS10A, LPPL_HUMAN, galectin-10, and GAL10. CLC gene orthologs have been reported in the mouse, rat and chimpanzee species. Some CLC antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4