Anti-SMC2 antibodies are used in the immunodetection of the protein structural maintenance of chromosomes 2. In humans, the canonical protein has a reported length of 1197 amino acid residues and a mass of 135.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the SMC protein family, SMC2 is reported to be a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. Synonyms for this target antigen include CAPE, SMC2L1, structural maintenance of chromosomes protein 2, SMC protein 2, SMC2 (structural maintenance of chromosomes 2, yeast)-like 1, and CAP-E. SMC2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of SMC2 antibodies in research. These antibodies are most commonly used in Western Blot experiments, among other applications.