Anti-ERCC2 antibodies are used in the immunodetection of the protein ERCC excision repair 2, TFIIH core complex helicase subunit. In humans, the canonical protein has a reported length of 760 amino acid residues and a mass of 86.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Helicase protein family, ERCC2 is known to be involved with pathways of aging and the apoptotic pathway. Synonyms for this target antigen include EM9, TFIIH, TTD, TTD1, XPD, general transcription and DNA repair factor IIH helicase subunit XPD, BTF2 p80, and COFS2. ERCC2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ERCC2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunofluorescence is also a common application.