Anti-ANK1 antibodies are used in the immunodetection of the protein ankyrin 1. In humans, the canonical protein has a reported length of 1881 amino acid residues and a mass of 206.3 kDa. Its subcellular localization is in the cytoplasm. Up to 23 different isoforms have been reported for this protein. It is notably expressed in the bone marrow and cerebellum. ANK1 is known to be involved with cytoskeleton organization and Golgi transport. Post-translational modifications have been described, including palmitoylation, protein cleavage and phosphorylation. Synonyms for this target antigen include SPH1, SPH2, ankyrin 1, erythrocytic, ankyrin-R, erythrocyte ankyrin, and ANK. ANK1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of ANK1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.