Anti-GJC1 antibodies are used in the immunodetection of the protein gap junction protein gamma 1. In humans, the canonical protein has a reported length of 396 amino acid residues and a mass of 45.5 kDa. Its subcellular localization is in the cell membrane. A member of the Connexin protein family, GJC1 is known to be involved with cell to cell signaling and chemical synaptic transmission. The GJC1 marker can be used to identify Pacemaker Cells and Pacemaker Cardiomyocytes.* Synonyms for this target antigen include GJA7, gap junction gamma-1 protein, CTC-296K1.4, connexin-45, gap junction alpha-7 protein, and CX45. GJC1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of GJC1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4