Anti-ME3 antibodies are used in the immunodetection of the protein malic enzyme 3. In humans, the canonical protein has a reported length of 604 amino acid residues and a mass of 67.1 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in organs with a low-division rate. A member of the Malic enzymes protein family, ME3 is known to catalyze the oxidative decarboxylation of (S)-malate to pyruvate using NADP(+) as a cofactor. Synonyms for this target antigen include NADP-dependent malic enzyme, mitochondrial, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), malic enzyme 3, NADP(+)-dependent, mitochondrial, and NADP-ME. ME3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of ME3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.