Anti-LETM1 antibodies are used in the immunodetection of the protein leucine zipper and EF-hand containing transmembrane protein 1. In humans, the canonical protein has a reported length of 739 amino acid residues and a mass of 83.4 kDa. Its subcellular localization is in the mitochondria. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the LETM1 protein family, LETM1 is known to play an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Synonyms for this target antigen include KHE, Mdm38, SLC55A1, mitochondrial proton/calcium exchanger protein, LETM1 and EF-hand domain-containing protein 1, mitochondrial, and CONDMIM. LETM1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of LETM1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.