Anti-IRS2 antibodies are used in the immunodetection of the protein insulin receptor substrate 2. In humans, the canonical protein has a reported length of 1338 amino acid residues and a mass of 137.3 kDa. Its subcellular localization is in the cytoplasm. It is notably expressed in many tissues, such as the breast, tonsil, and adrenal gland. IRS2 is believed to mediate the control of various cellular processes by insulin. IRS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 130 citations in the literature describe the use of IRS2 antibodies in research. Western Blot, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.