Anti-TYRO3 antibodies are used in the immunodetection of the protein TYRO3 protein tyrosine kinase. In humans, the canonical protein has a reported length of 890 amino acid residues and a mass of 96.9 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in the brain and lower levels in other tissues. A member of the Tyr protein kinase protein family, TYRO3 is a known receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. TYRO3 is also used as a cellular marker for characterizing microglia. Synonyms for this target antigen include Dtk, Etk-2, RSE, Rek, Sky, Tif, tyrosine-protein kinase receptor TYRO3, and BYK. TYRO3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 100 citations in the literature describe the use of TYRO3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.