Mouse Tyro3/Dtk Antibody AF759 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse Tyro3/Dtk Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF759
NCBI Gene AliasesDtk, etk2/tyro3, Rse, Brt, Sky, tk19-1, TK19-2, Tif, Etk-2
ApplicationsFlow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
TargetTyro3/Dtk
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
HostGoat
ReactivityMouse
NCBI Full Gene NameTYRO3 protein tyrosine kinase 3
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse Tyro3/Dtk, Ala31-Ser418, Accession # P55144
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion proteinNature medicineSeptember 1, 2022Jung H, Lee SY, Lim S, Choi HR, Choi Y, Kim M, Kim S, Lee Y, Han KH, Chung WS, et al.

(2) IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infectionPLoS neglected tropical diseasesDecember 1, 2019Rogers KJ, Brunton B, Mallinger L, Bohan D, Sevcik KM, Chen J, Ruggio N, Maury W.Biotechnology), anti-murine TIM-4 catalog number AF2826 (R&D Systems), anti-murine TYRO3 catalog number AF759 (R&D Systems), anti-murine MGL1/2 catalog number FAB4297P (R&D Systems). Cells were stained in FACS

(3) Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseasesThe Journal of experimental medicineSeptember 2, 2019Fujino N, Brand OJ, Morgan DJ, Fujimori T, Grabiec AM, Jagger CP, Maciewicz RA, Yamada M, Itakura K, Sugiura H, et al.anti-Axl (AF854, 4 µg/ml; R&D Systems); goat anti-Mertk (BAF591, 4 µg/ml; R&D Systems); goat anti-Tyro3 (AF759, 4 µg/ml; R&D Systems); goat anti-Gas6 (BAF986, 4 µg/ml; R&D Systems); rat anti-Ki67 (#13-5698 [SolA15],

(4) Gas6/TAM Receptors in Systemic Lupus ErythematosusDisease markersJanuary 1, 2019Cohen PL, Shao WH.ligands, PtdSer, and calcium ions [21]. Interestingly, the widely used goat anti-Mer (AF591) and anti-Axl (AF759) antibodies from R&D Systems induced receptor phosphorylation [23], but blocked receptor-mediated phagocytosis

(5) Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosisProceedings of the National Academy of Sciences of the United States of AmericaAugust 15, 2017Yanagihashi Y, Segawa K, Maeda R, Nabeshima YI, Nagata S.

(6) Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian BrainNeuronMay 3, 2017Voronova A, Yuzwa SA, Wang BS, Zahr S, Syal C, Wang J, Kaplan DR, Miller FD.

(7) Diversification of TAM receptor tyrosine kinase functionNature immunologyOctober 1, 2014Zagórska A, Través PG, Lew ED, Dransfield I, Lemke G.

(8) Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivitieseLifeSeptember 29, 2014Lew ED, Oh J, Burrola PG, Lax I, Zagórska A, Través PG, Schlessinger J, Lemke G.reagents Antibodies used were as follows: anti-Tyro3 (Santa Cruz, Dallas, TX, sc-1095, R&D Systems, Minneapolis, MN, AF759), anti-Axl (Santa Cruz sc-1097, R&D Systems AF854), anti-Mer (R&D Systems AF591), antiHA (Covance, Princeton,

(9) The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cellsNatureMarch 27, 2014Paolino M, Choidas A, Wallner S, Pranjic B, Uribesalgo I, Loeser S, Jamieson AM, Langdon WY, Ikeda F, Fededa JP, et al.

(10) The TAM-family receptor Mer mediates production of HGF through the RhoA-dependent pathway in response to apoptotic cellsMolecular biology of the cellAugust 1, 2012Park HJ, Baen JY, Lee YJ, Choi YH, Kang JL.(AF591), a goat polyclonal anti-mouse Axl antibody (AF854), a goat polyclonal anti-mouse Tyro3 antibody (AF759), and a normal goat IgG antibody (AB-108-C) were purchased from R&D Systems. In direct ELISAs and Western blots

(11) Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like regionThe Journal of neuroscience : the official journal of the Society for NeuroscienceNovember 17, 2010Zhong Z, Wang Y, Guo H, Sagare A, Fernández JA, Bell RD, Barrett TM, Griffin JH, Freeman RS, Zlokovic BV.

(12) Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptorBloodJune 10, 2010Zhu D, Wang Y, Singh I, Bell RD, Deane R, Zhong Z, Sagare A, Winkler EA, Zlokovic BV.

(13) Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responsesJournal of thrombosis and haemostasis : JTHApril 1, 2005Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA.

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Tyro3/Dtk Antibody

Tyro3/Dtk Antibody

Mouse Tyro3/Dtk Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

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Mouse Tyro3/Dtk Antibody from R&D Systems, a Bio-Techne Brand

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