Anti-PDK2 antibodies are used in the immunodetection of the protein pyruvate dehydrogenase kinase 2. In humans, the canonical protein has a reported length of 407 amino acid residues and a mass of 46.2 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in many tissues, with the highest level in the heart and skeletal muscle, intermediate levels in the brain, kidney, pancreas and liver, and low levels in the placenta and lung. A member of the PDK/BCKDK protein kinase protein family, PDK2 is a reported kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. Synonyms for this target antigen include PDKII, pyruvate dehydrogenase kinase, isozyme 2, PDH kinase 2, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial, and PDHK2. A number of PDK2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.