Anti-KRT2 antibodies are used in the immunodetection of the protein keratin 2. In humans, the canonical protein has a reported length of 639 amino acid residues and a mass of 65.4 kDa. Its subcellular localization is in the cytoplasm. It is notably expressed in the vagina, skin, esophagus, and cervix. A member of the Intermediate filament protein family, KRT2 is suspected to be contributes to terminal cornification. The KRT2 gene has been associated with the disease, Ichthyosis bullosa of Siemens. Synonyms for this target antigen include K2e, KRT2A, KRT2E, KRTE, keratin, type II cytoskeletal 2 epidermal, cytokeratin-2e, epithelial keratin-2e, and CK-2e. KRT2 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Over 300 citations in the literature describe the use of KRT2 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.