Anti-CAMK2B antibodies are used in the immunodetection of the protein calcium/calmodulin dependent protein kinase II beta. In humans, the canonical protein has a reported length of 666 amino acid residues and a mass of 72.7 kDa. Its subcellular localization is in the membrane and cytoplasm. Up to 8 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the CAMK Ser/Thr protein kinase protein family, CAMK2B is known to be involved with cell differentiation and nervous system development. Post-translational modifications have been described, including phosphorylation. The CAMK2B marker can be used to identify Neuro-Medullary Thymic Epithelial Cells.* Synonyms for this target antigen include CAMK2, CAMKB, CaMKIIbeta, MRD54, calcium/calmodulin-dependent protein kinase type II subunit beta, and CAM2. CAMK2B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4