Anti-ERCC8 antibodies are used in the immunodetection of the protein ERCC excision repair 8, CSA ubiquitin ligase complex subunit. In humans, the canonical protein has a reported length of 396 amino acid residues and a mass of 44.1 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. ERCC8 is known to be involved with DNA damage pathways and protein ubiquitination. The ERCC8 gene has been associated with the disease, Cockayne syndrome. Synonyms for this target antigen include CSA, UVSS2, DNA excision repair protein ERCC-8, Cockayne syndrome WD-repeat protein CSA, and CKN1. ERCC8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ERCC8 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.