Anti-GRM6 antibodies are used in the immunodetection of the protein glutamate metabotropic receptor 6. In humans, the canonical protein has a reported length of 877 amino acid residues and a mass of 95.5 kDa. Its subcellular localization is in the ER, Golgi, and cell membrane. It is notably expressed in melanocytes. A member of the G-protein coupled receptor 3 protein family, GRM6 is known to be involved with chemical synaptic transmission and eye development. Post-translational modifications have been described, including glycosylation. The GRM6 marker can be used to identify Retinal Bipolar Neuron.* Synonyms for this target antigen include GPRC1F, MGLUR6, mGlu6, metabotropic glutamate receptor 6, glutamate receptor, metabotropic 6, and CSNB1B. GRM6 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4